Develop, validate and improve quantitative methods and tools for accurate experimental design to enable tumour model translation in drug discovery and development.​

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Presentation: Translational PK/PD Modelling. UCB Pharma, Slough (11/2018) PDF (Part 1), PDF (Part 2)

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Data, R script: https://github.com/TheOpenProject/

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What is TOP Doing Now?

• Raise awareness of the importance of translational modelling

• Cell line / patient derived xenograft model: Characterise, Evaluate, Clinical Translation

• Syngeneic mouse model: Evaluate

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Who Should Contribute to TOP?

To rapidly develop affordable novel cancer treatments, a lot of good decisions need to be made fast. And this can only happen by using all accessible data in meaningful ways. Everyone has a role to play in The Open Project to make it happen.

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Do you like planning events?

• Organise TOP online meeting to discuss project progress and direction

• Organise workshops or meetups about TOP

• Help community members find the right conferences and submit proposals for speaking

Do you like to write?

• Write and improve the project’s documentation

• Curate a folder of examples showing how the project is used

• Start a newsletter for the project, or curate highlights from the mailing list

• Write tutorials for the project

• Write a translation for the project’s documentation

Do you like to design?

• Design a logo for TOP to make it recognisable

• Restructure layouts to improve the project’s usability

• Put together a style guide to help the project have a consistent visual design

Do you like mathematical/statistical modelling?

• Find an open issue to tackle

• Help develop a new story

• Source new open data

Do you like to code?

• Make codes run smoothly and faster across different platforms

• Improve tooling and testing

• Maintain the code so that it does not become obsolete

Do you like helping others?

• Review code on other people’s submissions

• Write tutorials for how a project can be used

• Offer to mentor another contributor

 

If your answer to any of these is "YES", get in touch now.

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The Benefits of Joining TOP

Improve existing skills

• Organise meetings and events

• Exchange codes with leading scientists in the field

• Better graphic design

• Good writing for clear communication

Meet like-minded pioneers

• Work with people you already know and feel comfortable working with

• Meet new people who share firm believe in open data and open science

• Warm, welcoming communities made of trusted, passionate people

• Gain lifelong friendships through intellectual and organisational contributions

Find mentors and teach others

• Explain how you do things

• Ask others for help

• Sense of fulfilment and achievement

Grow a reputation and a career

• Free, pro bono examples to take anywhere as a demonstration of what you can do

Learn people skills

• Practice leadership and management skills

• Resolve conflicts among people of different characters and backgrounds

• Organise teams of people

• Prioritise work

Make changes, even small ones

• You don’t have to become a lifelong contributor to enjoy participating in TOP

• Have you ever seen a typo, and wished someone would fix it? Here, you can do just that

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