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People with passion can change the world.

 

STEVE JOBS

Develop, validate and improve quantitative methods and tools for accurate experimental design to enable tumour model translation in drug discovery and development.​

Presentation: Translational PK/PD Modelling. UCB Pharma, Slough (11/2018) PDF (Part 1), PDF (Part 2)

Data, R script: https://github.com/TheOpenProject/

What is TOP Doing Now?

  • Raise awareness of the importance of translational modelling

  • Cell line / patient derived xenograft model: Characterise, Evaluate, Clinical Translation

  • Syngeneic mouse model: Evaluate

Who Should Contribute to TOP?

To rapidly develop affordable novel cancer treatments, a lot of good decisions need to be made fast. And this can only happen by using all accessible data in meaningful ways. Everyone has a role to play in The Open Project to make it happen.

Do you like planning events?

  • Organise TOP online meeting to discuss project progress and direction

  • Organise workshops or meetups about TOP

  • Help community members find the right conferences and submit proposals for speaking

Do you like to write?

  • Write and improve the project’s documentation

  • Curate a folder of examples showing how the project is used

  • Start a newsletter for the project, or curate highlights from the mailing list

  • Write tutorials for the project

  • Write a translation for the project’s documentation

Do you like to design?

  • Design a logo for TOP to make it recognisable

  • Restructure layouts to improve the project’s usability

  • Put together a style guide to help the project have a consistent visual design

Do you like mathematical/statistical modelling?

  • Find an open issue to tackle

  • Help develop a new story

  • Source new open data

Do you like to code?

  • Make codes run smoothly and faster across different platforms

  • Improve tooling and testing

  • Maintain the code so that it does not become obsolete

Do you like helping others?

  • Review code on other people’s submissions

  • Write tutorials for how a project can be used

  • Offer to mentor another contributor

 

If your answer to any of these is "YES", get in touch now.

The Benefits of Joining TOP

Improve existing skills

  • Organise meetings and events

  • Exchange codes with leading scientists in the field

  • Better graphic design

  • Good writing for clear communication

Meet like-minded pioneers

  • Work with people you already know and feel comfortable working with

  • Meet new people who share firm believe in open data and open science

  • Warm, welcoming communities made of trusted, passionate people

  • Gain lifelong friendships through intellectual and organisational contributions

Find mentors and teach others

  • Explain how you do things

  • Ask others for help

  • Sense of fulfilment and achievement

Grow a reputation and a career

  • Free, pro bono examples to take anywhere as a demonstration of what you can do

Learn people skills

  • Practice leadership and management skills

  • Resolve conflicts among people of different characters and backgrounds

  • Organise teams of people

  • Prioritise work

Make changes, even small ones

  • You don’t have to become a lifelong contributor to enjoy participating in TOP

  • Have you ever seen a typo, and wished someone would fix it? Here, you can do just that

 

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